Electron Microscopy Unit

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Electron Microscopy Unit

The Electron Microscopy Unit's objectives were to provide specialized diagnostic services to hospitals, enables rapid visualization of virus at high resolution during outbreak investigations by identifying viral morphology further confirming the presence of the virus, as well as to support and complement research activities.

In its diagnostic functions, the unit has been involved in the diagnosis of native kidney diseases and, in some instances, kidney transplants in Malaysia. These services, previously unavailable in any MOH hospitals, have made a significant contribution to the diagnosis of biopsy samples by complementing other diagnostic techniques, such as light microscopy and immunofluorescence, by providing ultrastructural details for accurate diagnosis.

The unit also supports and complements research activities in IMR, other institutions, and universities by providing consultations, technical expertise, and training on the application of EM to improve and strengthen research activities during proposal preparation and throughout the research process, from implementation to data analysis.

Executive Summary

Head of Electron Microscopy Unit

Mrs. Tengku Rogayah binti Tengku Abdul Rashid

BSc. Zoology (Hons) (UM, Malaysia), MSc. Entomology (UKM, Malaysia)

Google Scholar | ResearchGate | ORCID

Telephone: +603-3362 8942

Email: tg_rogayah@moh.gov.my

Mrs. Tengku Rogayah Binti Tengku Abdul Rashid
Mrs. Tengku Rogayah Binti Tengku Abdul Rashid

Human Resource Profile

02

Research Officers

01

Science Officer

02

Assistant Science Officers

02

Support Staffs

Focus Area

Disease Investigation & Diagnosis

Scope: Diagnostics

Highlights:

  • Rapid diagnosis of infectious disease outbreaks by enabling the direct visualization of viral particles in clinical samples

Discovery

Scope: Taxonomy / method development

Highlights:

  • Detailed visualization of vector anatomy and ultrastructure for understanding the compound effect on the vector morphology

  • Optimization of sample preparation and imaging techniques across a wide range of specimen types, including clinical samples, environmental samples, and biological tissues
  • Supports innovation in diagnostic and experimental protocols, thus accelerating research and the public health area

Disease Prevention

Scope: vaccine development

Highlights

  • Characterizing viral morphology, and assessing the integrity of vaccine candidates such as virus-like particles

Study Design

Guidance on research methodology, study design, and protocol development for the application of the EM technique in research and diagnostic

Area of Expertise

  • Development of protocol

  • Grant proposal development

Ultrastructure Description

Guidance to pathologist in the investigation of a disease related to biopsy samples by description of the ultrastructure of the organelle

Area of Expertise

  • Ultrastructural description

Gallery