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Endocrine & Metabolic Unit

Our research focuses on identifying biomarkers, developing community-based obesity intervention programs, and elucidating disease pathways to enable early detection, diagnosis, monitoring, and targeted therapy.

We employ various techniques in our research, including biochemistry analysis, cell culture, molecular techniques, animal models, and metabolomics. Our researchers are involved in studies aimed at identifying new biomarkers for the early detection and prognosis of Type 2 diabetes (T2DM). This includes an exploratory study on plasma N-glycan profiling as a potential T2DM signature. Additionally, we investigate the metabolic changes following metabolic surgery in obese diabetic patients using both metabolomic and molecular approaches.

The unit also examines the effects of lifestyle modifications, such as intermittent fasting, on inflammatory markers, lipid profiles, and metabolite profiles. Another area of expertise is the study of local functional foods and plant extracts for their antidiabetic properties, utilizing both in vivo and in vitro techniques.

Our unit continues to collaborate with other institutions in both the government and private sectors on relevant research projects. We aim to establish ourselves as a leading center of excellence in preclinical research on endocrinology and metabolic diseases.

Executive Summary

Head of Endocrine & Metabolic Unit

Dr Norhashimah binti Abu Seman

BSc, PhD.

Google Scholar | ResearchGate

Telephone: +603-33627827

Email: nor.hashimah@moh.gov.my

 

Dr Norhashimah binti Abu Seman
Dr Norhashimah binti Abu Seman

Human Resource Profile

01

Specialist

03

Medical Officers

08

Research Officers

07

Support Staffs

Focus Area

Discovery, Treatment & Management, Prediction: Diabetes

Scope: Metabolomics/Genomics, Functional food/Natural products – preclinical, Intervention

Highlights:

  • Genetic studies on diabetes complications

  • Metabolomics and molecular effects of metabolic surgery

  • Anti-diabetes properties of natural products and functional food

Discovery, Treatment & Management: Obesity

Scope: Metabolomics/Genomics, Biomarkers, Functional food /Natural products – preclinical, Effectiveness

Highlights

  • Community obesity intervention studies among school children, housewives, and in the workplace

  • Metabolomics and molecular effects of metabolic surgery

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