Endocrine Unit
Endocrine Unit
The Endocrine Unit serves as a reference laboratory for specialised diagnostic services in endocrinology and non-communicable diseases. It conducts biomedical research on new biomarkers in these fields. The unit provides various training programs in endocrinology and non-communicable diseases for researchers and officers from within and outside IMR, as well as for students from local and international higher education institutions. It also offers consultancy services in these areas to researchers, officers, and students both within and outside IMR.
Executive Summary
Head of Endocrine Unit
Dr. Saraswathy Apparow
MBBS (MAHE, India), MPath (Chemical Pathology) (UM, Malaysia)
Telephone: +603-2616 2636
Email: dr.saraswathy@moh.gov.my
Human Resource Profile
Specialists
Medical Officers
Support Staffs
Focus Area
Discovery, Investigations & Diagnostics, Treatment and Management, Prevention
Scope: Diabetes
Highlights
Identification of biomarkers
Test method development, evaluation and validation
Population based screening and epidemiology
Discovery, Investigations & Diagnostics, Treatment and Management
Scope: Rare endocrine genetic diseases
Highlights
Identification of biomarkers
Test method development, evaluation and validation
Population based screening and epidemiology
Functions
Serology
Test name: Immunoglobulin E
Description: Measure total and allergen-specific immunoglobulin E (IgE) to detect sensitisation to aeroallergens, foods, and drug including component resolved diagnosis.
Cellular
Test name: Basophil Activation Test
Description: Evaluate allergen-induced immune activation
Biomarkers
Test name: Tryptase, Eosinophils Cationic Protein
Description: Measure biomarkers released by activated mast cells and eosinophils, key cells involved in allergy and inflammation. By analysing these biomarkers, clinicians can gain valuable information about the inflammatory pathways,providing accurate diagnosis, and treatment monitoring.
Specialised Endocrine Diagnostics
Expert in providing consultation, data interpretation, and advisory support to ensure high-quality outcomes in specialised endocrine diseases for the diagnosis and management.
Area of Expertise
Immunoassays, including ELISA and CLIA techniques
Specialised Endocrine Research
Expert guidance on specialised endocrine diseases for research methodology, study design, and protocol development.
Area of Expertise
Inherited diabetes and autoimmune diabetes and MODY characterisation, and standardisation including CLIA and ELISA and molecular analysis
congenital adrenal hyperplasia and inherited adrenal disorders characterisation, and standardisation including immunoassay , LCMS and molecular analysis
Expertise in bioinformatics data analysis of computational genomics datasets to identify disease-causing variants, pathways, and potential therapeutic targets